General Structure Information
| PDB ID | 3dh1 |
| HGNC Gene Label(s) | ADAT2 |
| Structure Name | crystal structure of human trna-specific adenosine-34 deaminase subunit adat2 |
| Resolution | 2.8Å |
| Reference | AUTH M.WELIN,L.TRESAUGUES,J.ANDERSSON,C.H.ARROWSMITH,H.BERGLUND,AUTH 2 R.COLLINS,L.G.DAHLGREN,A.M.EDWARDS,S.FLODIN,A.FLORES,AUTH 3 S.GRASLUND,M.HAMMARSTROM,A.JOHANSSON,I.JOHANSSON,T.KARLBERG,AUTH 4 T.KOTENYOVA,L.LEHTIO,M.MOCHE,M.E.NILSSON,T.NYMAN,K.OLESEN,AUTH 5 C.PERSSON,J.SAGEMARK,H.SCHUELER,A.G.THORSELL,S.VAN DER BERG,AUTH 6 M.WISNIEWSKA,M.WIKSTROM,P.NORDLUNDTITL CRYSTAL STRUCTURE OF HUMAN TRNA-SPECIFIC ADENOSINE-34TITL 2 DEAMINASE SUBUNIT ADAT2.REF TO BE PUBLISHEDREFN |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 154 |
| Number Of SNVs | 37 |
| Number Of Permutations | 11186 |
| Optimal Distance Threshold | 10.0 |
| K Statistic | 0.099 |
| p-value | 0.592 |
COSMIC
| Number Of Residues | 154 |
| Number Of SNVs | 3 |
| Number Of Permutations | 140 |
| Optimal Distance Threshold | 18.0 |
| K Statistic | 0.667 |
| p-value | 0.905 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 37 |
| Number Of COSMIC SNVs | 3 |
| Optimal Distance Threshold | 15.0 |
| K Statistic | -0.291 |
| p-value | 1.0 |
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
