General Structure Information
| PDB ID | 3og4 |
| HGNC Gene Label(s) | IFNLR1 |
| Structure Name | the crystal structure of human interferon lambda 1 complexed with its high affinity receptor in space group p21212 |
| Resolution | 2.16Å |
| Reference | AUTH Z.J.MIKNIS,E.MAGRACHEVA,W.LI,A.ZDANOV,S.V.KOTENKO,A.WLODAWERTITL CRYSTAL STRUCTURE OF THE COMPLEX OF HUMAN INTERFERON-LAMBDA1TITL 2 WITH ITS HIGH AFFINITY RECEPTOR INTERFERON-LAMBDAR1.REF J.MOL.BIOL. V. 404 650 2010REFN ISSN 0022-2836PMID 20934432DOI 10.1016/J.JMB.2010.09.068 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 197 |
| Number Of SNVs | 40 |
| Number Of Permutations | 8227 |
| Optimal Distance Threshold | 7.0 |
| K Statistic | 0.044 |
| p-value | 0.696 |
COSMIC
| Number Of Residues | 197 |
| Number Of SNVs | 4 |
| Number Of Permutations | 108 |
| Optimal Distance Threshold | 12.0 |
| K Statistic | 0.333 |
| p-value | 0.311 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 40 |
| Number Of COSMIC SNVs | 4 |
| Optimal Distance Threshold | 12.0 |
| K Statistic | 0.197 |
| p-value | 0.469 |
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
