4I7C.C | SIAH1

General Structure Information

PDB ID 4i7c
HGNC Gene Label(s) SIAH1
Structure Name siah1 mutant bound to synthetic peptide (ace)klrpv(23p)mvrpwvr
Resolution 2.8Å
Reference AUTH J.L.STEBBINS,E.SANTELLI,Y.FENG,S.K.DE,A.PURVES,AUTH 2 K.MOTAMEDCHABOKI,B.WU,Z.A.RONAI,R.C.LIDDINGTON,M.PELLECCHIATITL STRUCTURE-BASED DESIGN OF COVALENT SIAH INHIBITORS.REF CHEM.BIOL. V. 20 973 2013REFN ISSN 1074-5521PMID 23891150DOI 10.1016/J.CHEMBIOL.2013.06.008

Variant Set Distributions

ExAC Variants

Number Of Residues 190
Number Of SNVs 9
Number Of Permutations 6917
Optimal Distance Threshold 7.0
K Statistic 0.0
p-value 0.56

Mapped Variants

[+] ExAC Missense Variants