General Structure Information
| PDB ID | 3czv |
| HGNC Gene Label(s) | CA13 |
| Structure Name | crystal structure of the human carbonic anhydrase xiii in complex with acetazolamide |
| Resolution | 2.0Å |
| Reference | AUTH A.DI FIORE,S.M.MONTI,M.HILVO,S.PARKKILA,V.ROMANO,A.SCALONI,AUTH 2 C.PEDONE,A.SCOZZAFAVA,C.T.SUPURAN,G.DE SIMONETITL CRYSTAL STRUCTURE OF HUMAN CARBONIC ANHYDRASE XIII AND ITSTITL 2 COMPLEX WITH THE INHIBITOR ACETAZOLAMIDE.REF PROTEINS V. 74 164 2008REFN ISSN 0887-3585PMID 18618712DOI 10.1002/PROT.22144 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 258 |
| Number Of SNVs | 73 |
| Number Of Permutations | 26398 |
| Optimal Distance Threshold | 9.0 |
| K Statistic | 0.048 |
| p-value | 0.354 |
COSMIC
| Number Of Residues | 258 |
| Number Of SNVs | 4 |
| Number Of Permutations | 1 |
| Optimal Distance Threshold | 13.0 |
| K Statistic | 0.167 |
| p-value | 1.0 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 73 |
| Number Of COSMIC SNVs | 4 |
| Optimal Distance Threshold | 19.0 |
| K Statistic | 0.512 |
| p-value | 0.297 |
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
