General Structure Information
| PDB ID | 4l7e |
| HGNC Gene Label(s) | HDDC2 |
| Structure Name | three dimensional structure of mutant d78a of human hd domain- containing protein 2, genomics consortium (nesg) target hr6723 |
| Resolution | 2.23Å |
| Reference | AUTH A.KUZIN,M.SU,A..YAKUNIN,N.BELOGLAZOVA,J.SEETHARAMAN,AUTH 2 M.MAGLAQUI,R.XIAO,D.LEE,G.BROWN,R.FLICK,J.K.EVERETT,AUTH 3 T.B.ACTON,G.T.MONTELIONE,J.F.HUNT,L.TONG,AUTH 4 NORTHEAST STRUCTURAL GENOMICS CONSORTIUM (NESG)TITL NORTHEAST STRUCTURAL GENOMICS CONSORTIUM TARGET HR6723REF TO BE PUBLISHEDREFN |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 184 |
| Number Of SNVs | 48 |
| Number Of Permutations | 7902 |
| Optimal Distance Threshold | 20.0 |
| K Statistic | 0.489 |
| p-value | 0.033 |
COSMIC
| Number Of Residues | 184 |
| Number Of SNVs | 9 |
| Number Of Permutations | 1232 |
| Optimal Distance Threshold | 6.0 |
| K Statistic | 0.056 |
| p-value | 0.787 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 48 |
| Number Of COSMIC SNVs | 9 |
| Optimal Distance Threshold | 23.0 |
| K Statistic | -0.173 |
| p-value | 0.493 |