General Structure Information
| PDB ID | 2wqz |
| HGNC Gene Label(s) | NLGN4X |
| Structure Name | crystal structure of synaptic protein neuroligin-4 in complex with neurexin-beta 1: alternative refinement |
| Resolution | 3.9Å |
| Reference | AUTH I.P.FABRICHNY,P.LEONE,G.SULZENBACHER,D.COMOLETTI,M.T.MILLER,AUTH 2 P.TAYLOR,Y.BOURNE,P.MARCHOTTITL STRUCTURAL ANALYSIS OF THE SYNAPTIC PROTEIN NEUROLIGIN ANDTITL 2 ITS BETA-NEUREXIN COMPLEX: DETERMINANTS FOR FOLDING ANDTITL 3 CELL ADHESION.REF NEURON V. 56 979 2007REFN ISSN 0896-6273PMID 18093521DOI 10.1016/J.NEURON.2007.11.013 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 538 |
| Number Of SNVs | 61 |
| Number Of Permutations | 12548 |
| Optimal Distance Threshold | 8.0 |
| K Statistic | 0.031 |
| p-value | 0.188 |
COSMIC
| Number Of Residues | 538 |
| Number Of SNVs | 17 |
| Number Of Permutations | 9875 |
| Optimal Distance Threshold | 4.0 |
| K Statistic | 0.007 |
| p-value | 0.092 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 61 |
| Number Of COSMIC SNVs | 15 |
| Optimal Distance Threshold | 19.0 |
| K Statistic | 0.075 |
| p-value | 0.356 |