General Structure Information
| PDB ID | 4n48 |
| HGNC Gene Label(s) | CMTR1 |
| Structure Name | cap-specific mrna (nucleoside-2-o-)-methyltransferase 1 protein in complex with capped rna fragment |
| Resolution | 2.7Å |
| Reference | AUTH M.SMIETANSKI,M.WERNER,E.PURTA,K.H.KAMINSKA,J.STEPINSKI,AUTH 2 E.DARZYNKIEWICZ,M.NOWOTNY,J.M.BUJNICKITITL STRUCTURAL ANALYSIS OF HUMAN 2-O-RIBOSE METHYLTRANSFERASESTITL 2 INVOLVED IN MRNA CAP STRUCTURE FORMATION.REF NAT COMMUN V. 5 3004 2014REFN ESSN 2041-1723PMID 24402442DOI 10.1038/NCOMMS4004 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 401 |
| Number Of SNVs | 60 |
| Number Of Permutations | 9413 |
| Optimal Distance Threshold | 11.0 |
| K Statistic | 0.07 |
| p-value | 0.517 |
COSMIC
| Number Of Residues | 401 |
| Number Of SNVs | 3 |
| Number Of Permutations | 255 |
| Optimal Distance Threshold | 20.0 |
| K Statistic | 0.667 |
| p-value | 0.38 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 60 |
| Number Of COSMIC SNVs | 3 |
| Optimal Distance Threshold | 20.0 |
| K Statistic | 0.401 |
| p-value | 0.412 |