General Structure Information
| PDB ID | 2ysm |
| HGNC Gene Label(s) | KMT2C |
| Structure Name | solution structure of the first and second phd domain from myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog |
| Resolution | -1.0Å |
| Reference | AUTH X.R.QIN,F.HAYASHI,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE FIRST AND SECOND PHDTITL 2 DOMAIN FROM MYELOID/LYMPHOID OR MIXED-LINEAGETITL 3 LEUKEMIA PROTEIN 3 HOMOLOGREF TO BE PUBLISHEDREFN |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 98 |
| Number Of SNVs | 5 |
| Number Of Permutations | 314 |
| Optimal Distance Threshold | 6.0 |
| K Statistic | 0.1 |
| p-value | 0.497 |
COSMIC
| Number Of Residues | 98 |
| Number Of SNVs | 9 |
| Number Of Permutations | 1790 |
| Optimal Distance Threshold | 18.0 |
| K Statistic | 0.306 |
| p-value | 0.138 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 5 |
| Number Of COSMIC SNVs | 7 |
| Optimal Distance Threshold | 6.0 |
| K Statistic | -0.1 |
| p-value | 0.6 |
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
