General Structure Information
| PDB ID | 3v42 |
| HGNC Gene Label(s) | FLCN |
| Structure Name | crystal structure of renal tumor suppressor protein, folliculin |
| Resolution | 2.0Å |
| Reference | AUTH R.K.NOOKALA,L.LANGEMEYER,A.PACITTO,B.OCHOA-MONTANO,AUTH 2 J.C.DONALDSON,B.K.BLASZCZYK,D.Y.CHIRGADZE,F.A.BARR,AUTH 3 J.F.BAZAN,T.L.BLUNDELLTITL CRYSTAL STRUCTURE OF FOLLICULIN REVEALS A HIDDENN FUNCTIONTITL 2 IN GENETICALLY INHERITED RENAL CANCER.REF OPEN BIOL V. 2 20071 2012REFNPMID 22977732DOI 10.1098/RSOB.120071 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 196 |
| Number Of SNVs | 53 |
| Number Of Permutations | 26996 |
| Optimal Distance Threshold | 6.0 |
| K Statistic | 0.025 |
| p-value | 0.645 |
COSMIC
| Number Of Residues | 196 |
| Number Of SNVs | 4 |
| Number Of Permutations | 33 |
| Optimal Distance Threshold | 9.0 |
| K Statistic | 0.333 |
| p-value | 0.068 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 53 |
| Number Of COSMIC SNVs | 4 |
| Optimal Distance Threshold | 9.0 |
| K Statistic | 0.275 |
| p-value | 0.065 |