General Structure Information
| PDB ID | 3smp |
| HGNC Gene Label(s) | PANK1 |
| Structure Name | monoclinic crystal structure of human pantothenate kinase 1 alpha |
| Resolution | 1.9Å |
| Reference | AUTH X.GUAN,W.TEMPEL,B.HONG,A.K.WERNIMONT,C.H.ARROWSMITH,AUTH 2 A.M.EDWARDS,C.BOUNTRA,J.WEIGELT,H.PARKTITL MONOCLINIC CRYSTAL STRUCTURE OF HUMAN PANTOTHENATE KINASE 1TITL 2 ALPHAREF TO BE PUBLISHEDREFN |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 363 |
| Number Of SNVs | 58 |
| Number Of Permutations | 42286 |
| Optimal Distance Threshold | 6.0 |
| K Statistic | 0.012 |
| p-value | 0.929 |
COSMIC
| Number Of Residues | 363 |
| Number Of SNVs | 3 |
| Number Of Permutations | 27 |
| Optimal Distance Threshold | 19.0 |
| K Statistic | 0.333 |
| p-value | 1.0 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 58 |
| Number Of COSMIC SNVs | 3 |
| Optimal Distance Threshold | 37.0 |
| K Statistic | -0.408 |
| p-value | 0.84 |
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
