General Structure Information
| PDB ID | 1z9m |
| HGNC Gene Label(s) | CADM3 |
| Structure Name | crystal structure of nectin-like molecule-1 protein domain 1 |
| Resolution | 2.4Å |
| Reference | AUTH X.DONG,F.XU,Y.GONG,J.GAO,P.LIN,T.CHEN,Y.PENG,AUTH 2 B.QIANG,J.YUAN,X.PENG,Z.RAOTITL CRYSTAL STRUCTURE OF THE V DOMAIN OF HUMANTITL 2 NECTIN-LIKE MOLECULE-1/SYNCAM3/TSLL1/IGSF4B, ATITL 3 NEURAL TISSUE-SPECIFIC IMMUNOGLOBULIN-LIKETITL 4 CELL-CELL ADHESION MOLECULEREF J.BIOL.CHEM. V. 281 10610 2006REFN ISSN 0021-9258PMID 16467305DOI 10.1074/JBC.M513459200 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 104 |
| Number Of SNVs | 22 |
| Number Of Permutations | 3166 |
| Optimal Distance Threshold | 11.0 |
| K Statistic | 0.238 |
| p-value | 0.569 |
COSMIC
| Number Of Residues | 104 |
| Number Of SNVs | 6 |
| Number Of Permutations | 3007 |
| Optimal Distance Threshold | 14.0 |
| K Statistic | 0.133 |
| p-value | 0.357 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 22 |
| Number Of COSMIC SNVs | 4 |
| Optimal Distance Threshold | 5.0 |
| K Statistic | 0.149 |
| p-value | 0.839 |
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
