General Structure Information
| PDB ID | 3hhc |
| HGNC Gene Label(s) | IFNL3 |
| Structure Name | interferon-lambda is functionally an interferon but structurally related to the il-10 family |
| Resolution | 2.8Å |
| Reference | AUTH H.H.GAD,C.DELLGREN,O.J.HAMMING,S.VENDS,S.R.PALUDAN,AUTH 2 R.HARTMANNTITL INTERFERON-{LAMBDA} IS FUNCTIONALLY AN INTERFERONTITL 2 BUT STRUCTURALLY RELATED TO THE INTERLEUKIN-10TITL 3 FAMILYREF J.BIOL.CHEM. V. 284 20869 2009REFN ISSN 0021-9258PMID 19457860DOI 10.1074/JBC.M109.002923 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 157 |
| Number Of SNVs | 36 |
| Number Of Permutations | 10810 |
| Optimal Distance Threshold | 8.0 |
| K Statistic | 0.063 |
| p-value | 0.973 |
COSMIC
| Number Of Residues | 157 |
| Number Of SNVs | 9 |
| Number Of Permutations | 3381 |
| Optimal Distance Threshold | 10.0 |
| K Statistic | 0.167 |
| p-value | 0.574 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 36 |
| Number Of COSMIC SNVs | 8 |
| Optimal Distance Threshold | 10.0 |
| K Statistic | 0.083 |
| p-value | 0.941 |