General Structure Information
| PDB ID | 4c8d |
| HGNC Gene Label(s) | KDM3B |
| Structure Name | crystal structure of jmjc domain of human histone 3 lysine- specific demethylase 3b (kdm3b) |
| Resolution | 2.18Å |
| Reference | AUTH M.VOLLMAR,C.JOHANSSON,C.GILEADI,S.GOUBIN,A.SZYKOWSKA,AUTH 2 T.KROJER,L.CRAWLEY,F.VON DELFT,C.H.ARROWSMITH,C.BOUNTRA,AUTH 3 A.EDWARDS,U.OPPERMANNTITL CRYSTAL STRUCTURE OF JMJC DOMAIN OF HUMAN HISTONE 3TITL 2 LYSINE-SPECIFIC DEMETHYLASE 3B (KDM3B)REF TO BE PUBLISHEDREFN |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 332 |
| Number Of SNVs | 24 |
| Number Of Permutations | 3039 |
| Optimal Distance Threshold | 6.0 |
| K Statistic | 0.025 |
| p-value | 0.931 |
COSMIC
| Number Of Residues | 332 |
| Number Of SNVs | 9 |
| Number Of Permutations | 3084 |
| Optimal Distance Threshold | 18.0 |
| K Statistic | 0.306 |
| p-value | 0.775 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 24 |
| Number Of COSMIC SNVs | 8 |
| Optimal Distance Threshold | 21.0 |
| K Statistic | 0.179 |
| p-value | 0.336 |
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
