General Structure Information
| PDB ID | 2jii |
| HGNC Gene Label(s) | VRK3 |
| Structure Name | structure of vaccinia related kinase 3 |
| Resolution | 2.0Å |
| Reference | AUTH E.D.SCHEEFF,J.ESWARAN,G.BUNKOCZI,S.KNAPP,G.MANNINGTITL STRUCTURE OF THE PSEUDOKINASE VRK3 REVEALS A DEGRADEDTITL 2 CATALYTIC SITE, A HIGHLY CONSERVED KINASE FOLD, AND ATITL 3 PUTATIVE REGULATORY BINDING SITE.REF STRUCTURE V. 17 128 2009REFN ISSN 0969-2126PMID 19141289DOI 10.1016/J.STR.2008.10.018 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 316 |
| Number Of SNVs | 88 |
| Number Of Permutations | 10249 |
| Optimal Distance Threshold | 9.0 |
| K Statistic | 0.038 |
| p-value | 0.926 |
COSMIC
| Number Of Residues | 316 |
| Number Of SNVs | 3 |
| Number Of Permutations | 295 |
| Optimal Distance Threshold | 49.0 |
| K Statistic | 0.667 |
| p-value | 0.027 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
