General Structure Information
| PDB ID | 3ihy |
| HGNC Gene Label(s) | PIK3C3 |
| Structure Name | human pik3c3 crystal structure |
| Resolution | 2.8Å |
| Reference | AUTH M.I.SIPONEN,L.TRESAUGUES,C.H.ARROWSMITH,H.BERGLUND,AUTH 2 C.BOUNTRA,R.COLLINS,A.M.EDWARDS,S.FLODIN,A.FLORES,AUTH 3 S.GRASLUND,M.HAMMARSTROM,A.JOHANSSON,I JOHANSSON,AUTH 4 T.KARLBERG,T.KOTENYOVA,A.KOTZSCH,T.KRAGH NIELSEN,AUTH 5 M.MOCHE,T.NYMAN,C.PERSSON,A.K.ROOS,J.SAGEMARK,AUTH 6 H.SCHUELER,P.SCHUTZ,A.G.THORSELL,S.VAN DEN BERG,AUTH 7 J.WEIGELT,M.WELIN,M.WISNIEWSKA,P.NORDLUNDTITL HUMAN PIK3C3 CRYSTAL STRUCTUREREF TO BE PUBLISHEDREFN |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 535 |
| Number Of SNVs | 85 |
| Number Of Permutations | 43855 |
| Optimal Distance Threshold | 24.0 |
| K Statistic | 0.248 |
| p-value | 0.109 |
COSMIC
| Number Of Residues | 535 |
| Number Of SNVs | 7 |
| Number Of Permutations | 5167 |
| Optimal Distance Threshold | 26.0 |
| K Statistic | 0.143 |
| p-value | 0.153 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 85 |
| Number Of COSMIC SNVs | 5 |
| Optimal Distance Threshold | 34.0 |
| K Statistic | -0.187 |
| p-value | 0.577 |
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
