General Structure Information
| PDB ID | 2dyp |
| HGNC Gene Label(s) | LILRB2 |
| Structure Name | crystal structure of lilrb2(lir2/ilt4/cd85d) complexed with hla-g |
| Resolution | 2.5Å |
| Reference | AUTH M.SHIROISHI,K.KUROKI,L.RASUBALA,K.TSUMOTO,AUTH 2 I.KUMAGAI,E.KURIMOTO,K.KATO,D.KOHDA,K.MAENAKATITL STRUCTURAL BASIS FOR RECOGNITION OF THETITL 2 NONCLASSICAL MHC MOLECULE HLA-G BY THE LEUKOCYTETITL 3 IG-LIKE RECEPTOR B2 (LILRB2/LIR2/ILT4/CD85D)REF PROC.NATL.ACAD.SCI.USA V. 103 16412 2006REFN ISSN 0027-8424PMID 17056715DOI 10.1073/PNAS.0605228103 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 185 |
| Number Of SNVs | 57 |
| Number Of Permutations | 25241 |
| Optimal Distance Threshold | 10.0 |
| K Statistic | 0.08 |
| p-value | 0.731 |
COSMIC
| Number Of Residues | 185 |
| Number Of SNVs | 9 |
| Number Of Permutations | 8216 |
| Optimal Distance Threshold | 4.0 |
| K Statistic | 0.028 |
| p-value | 0.84 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 57 |
| Number Of COSMIC SNVs | 6 |
| Optimal Distance Threshold | 30.0 |
| K Statistic | -0.268 |
| p-value | 0.16 |
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
