General Structure Information
| PDB ID | 2m5v |
| HGNC Gene Label(s) | NLRP10 |
| Structure Name | three-dimensional structure of human nlrp10/pynod pyrin domain |
| Resolution | -1.0Å |
| Reference | AUTH M.Y.SU,C.I.KUO,C.F.CHANG,C.I.CHANGTITL THREE-DIMENSIONAL STRUCTURE OF HUMAN NLRP10/PYNOD PYRINTITL 2 DOMAIN REVEALS A HOMOTYPIC INTERACTION SITE DISTINCT FROMTITL 3 ITS MOUSE HOMOLOGUE.REF PLOS ONE V. 8 67843 2013REFN ESSN 1932-6203PMID 23861819DOI 10.1371/JOURNAL.PONE.0067843 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 100 |
| Number Of SNVs | 25 |
| Number Of Permutations | 9174 |
| Optimal Distance Threshold | 7.0 |
| K Statistic | 0.08 |
| p-value | 0.349 |
COSMIC
| Number Of Residues | 100 |
| Number Of SNVs | 3 |
| Number Of Permutations | 1 |
| Optimal Distance Threshold | 8.0 |
| K Statistic | 0.333 |
| p-value | 1.0 |
Ripley’s K Analysis Plots
ExACCOSMIC


Variant Set Comparisons
Cosmic vs. ExAC

Pathogenic Proximity Analysis
COSMIC PathProx Analysis

