General Structure Information
| PDB ID | 3p2t |
| HGNC Gene Label(s) | LILRB4 |
| Structure Name | crystal structure of leukocyte ig-like receptor lilrb4 (ilt3/lir- 5/cd85k) |
| Resolution | 1.7Å |
| Reference | AUTH H.CHENG,F.MOHAMMED,G.NAM,Y.CHEN,J.QI,L.I.GARNER,R.L.ALLEN,AUTH 2 J.YAN,B.E.WILLCOX,G.F.GAOTITL CRYSTAL STRUCTURE OF LEUKOCYTE IG-LIKE RECEPTOR LILRB4TITL 2 (ILT3/LIR-5/CD85K): A MYELOID INHIBITORY RECEPTOR INVOLVEDTITL 3 IN IMMUNE TOLERANCEREF J.BIOL.CHEM. V. 286 18013 2011REFN ISSN 0021-9258PMID 21454581DOI 10.1074/JBC.M111.221028 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 194 |
| Number Of SNVs | 59 |
| Number Of Permutations | 11607 |
| Optimal Distance Threshold | 14.0 |
| K Statistic | 0.177 |
| p-value | 0.352 |
COSMIC
| Number Of Residues | 194 |
| Number Of SNVs | 5 |
| Number Of Permutations | 1203 |
| Optimal Distance Threshold | 7.0 |
| K Statistic | 0.1 |
| p-value | 0.831 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 59 |
| Number Of COSMIC SNVs | 5 |
| Optimal Distance Threshold | 32.0 |
| K Statistic | -0.294 |
| p-value | 0.634 |
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
