General Structure Information
| PDB ID | 2yz8 |
| HGNC Gene Label(s) | OBSCN |
| Structure Name | crystal structure of the 32th ig-like domain of human obscurin (kiaa1556) |
| Resolution | 2.0Å |
| Reference | AUTH S.SAIJO,N.OHSAWA,A.NISHINO,S.KISHISHITA,L.CHEN,Z.Q.FU,AUTH 2 J.CHRZAS,B.C.WANG,M.SHIROUZU,S.YOKOYAMATITL CRYSTAL STRUCTURE OF THE 32TH IG-LIKE DOMAIN OF HUMANTITL 2 OBSCURIN (KIAA1556)REF TO BE PUBLISHEDREFN |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 89 |
| Number Of SNVs | 29 |
| Number Of Permutations | 3098 |
| Optimal Distance Threshold | 7.0 |
| K Statistic | 0.057 |
| p-value | 0.16 |
COSMIC
| Number Of Residues | 89 |
| Number Of SNVs | 3 |
| Number Of Permutations | 18 |
| Optimal Distance Threshold | 17.0 |
| K Statistic | 0.333 |
| p-value | 1.0 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 29 |
| Number Of COSMIC SNVs | 3 |
| Optimal Distance Threshold | 18.0 |
| K Statistic | 0.421 |
| p-value | 0.674 |
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
