General Structure Information
| PDB ID | 3hzj |
| HGNC Gene Label(s) | RABGAP1L |
| Structure Name | crystal structure of the rabgap domain of the rabgap1l protein |
| Resolution | 2.3Å |
| Reference | AUTH L.NEDYALKOVA,W.TEMPEL,Y.TONG,N.ZHONG,F.MACKENZIE,AUTH 2 C.H.ARROWSMITH,A.M.EDWARDS,C.BOUNTRA,J.WEIGELT,AUTH 3 A.BOCHKAREV,H.PARKTITL CRYSTAL STRUCTURE OF THE RABGAP DOMAIN OF THETITL 2 RABGAP1L PROTEINREF TO BE PUBLISHEDREFN |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 280 |
| Number Of SNVs | 53 |
| Number Of Permutations | 6543 |
| Optimal Distance Threshold | 17.0 |
| K Statistic | 0.188 |
| p-value | 0.022 |
COSMIC
| Number Of Residues | 280 |
| Number Of SNVs | 3 |
| Number Of Permutations | 17 |
| Optimal Distance Threshold | 12.0 |
| K Statistic | 0.333 |
| p-value | 0.548 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 53 |
| Number Of COSMIC SNVs | 3 |
| Optimal Distance Threshold | 12.0 |
| K Statistic | 0.253 |
| p-value | 0.497 |
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
