4JRA.D | SV2C

General Structure Information

PDB ID 4jra
HGNC Gene Label(s) SV2C
Structure Name crystal structure of the botulinum neurotoxin a receptor-binding domain in complex with the luminal domain of sv2c
Resolution 2.3Å
Reference AUTH R.M.BENOIT,D.FREY,M.HILBERT,J.T.KEVENAAR,M.M.WIESER,AUTH 2 C.U.STIRNIMANN,D.MCMILLAN,T.CESKA,F.LEBON,R.JAUSSI,AUTH 3 M.O.STEINMETZ,G.F.SCHERTLER,C.C.HOOGENRAAD,G.CAPITANI,AUTH 4 R.A.KAMMERERTITL STRUCTURAL BASIS FOR RECOGNITION OF SYNAPTIC VESICLE PROTEINTITL 2 2C BY BOTULINUM NEUROTOXIN A.REF NATURE V. 505 108 2014REFN ISSN 0028-0836PMID 24240280DOI 10.1038/NATURE12732

Variant Set Distributions

ExAC Variants

Number Of Residues 93
Number Of SNVs 24
Number Of Permutations 1629
Optimal Distance Threshold 6.0
K Statistic 0.025
p-value 0.657

Mapped Variants

[+] ExAC Missense Variants