General Structure Information
| PDB ID | 1wis |
| HGNC Gene Label(s) | SDK2 |
| Structure Name | solution structure of the fifth fniii domain from human kiaa1514 protein |
| Resolution | -1.0Å |
| Reference | AUTH T.SUETAKE,F.HAYASHI,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE FIFTH FNIII DOMAIN FROMTITL 2 HUMAN KIAA1514 PROTEINREF TO BE PUBLISHEDREFN |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 111 |
| Number Of SNVs | 22 |
| Number Of Permutations | 5365 |
| Optimal Distance Threshold | 6.0 |
| K Statistic | 0.017 |
| p-value | 0.518 |
COSMIC
| Number Of Residues | 111 |
| Number Of SNVs | 3 |
| Number Of Permutations | 1 |
| Optimal Distance Threshold | 16.0 |
| K Statistic | 0.333 |
| p-value | 1.0 |
Ripley’s K Analysis Plots
ExACCOSMIC


Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 22 |
| Number Of COSMIC SNVs | 4 |
| Optimal Distance Threshold | 10.0 |
| K Statistic | -0.121 |
| p-value | 0.753 |
Pathogenic Proximity Analysis
COSMIC PathProx Analysis

