General Structure Information
| PDB ID | 2h8k |
| HGNC Gene Label(s) | SULT1C3 |
| Structure Name | human sulfotranferase sult1c3 in complex with pap |
| Resolution | 3.2Å |
| Reference | AUTH A.ALLALI-HASSANI,P.W.PAN,L.DOMBROVSKI,AUTH 2 R.NAJMANOVICH,W.TEMPEL,A.DONG,P.LOPPNAU,F.MARTIN,AUTH 3 J.THORNTON,J.THONTON,A.M.EDWARDS,A.BOCHKAREV,AUTH 4 A.N.PLOTNIKOV,M.VEDADI,C.H.ARROWSMITHTITL STRUCTURAL AND CHEMICAL PROFILING OF THE HUMANTITL 2 CYTOSOLIC SULFOTRANSFERASES.REF PLOS BIOL. V. 5 E97 2007REFN ISSN 1544-9173PMID 17425406DOI 10.1371/JOURNAL.PBIO.0050097 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 245 |
| Number Of SNVs | 60 |
| Number Of Permutations | 5194 |
| Optimal Distance Threshold | 8.0 |
| K Statistic | 0.045 |
| p-value | 0.366 |
COSMIC
| Number Of Residues | 245 |
| Number Of SNVs | 6 |
| Number Of Permutations | 1198 |
| Optimal Distance Threshold | 20.0 |
| K Statistic | 0.067 |
| p-value | 0.024 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 60 |
| Number Of COSMIC SNVs | 6 |
| Optimal Distance Threshold | 20.0 |
| K Statistic | -0.312 |
| p-value | 0.011 |