General Structure Information
| PDB ID | 2hvz |
| HGNC Gene Label(s) | SRSF7 |
| Structure Name | solution structure of the rrm domain of sr rich factor 9g8 |
| Resolution | -1.0Å |
| Reference | AUTH Y.HARGOUS,G.M.HAUTBERGUE,A.M.TINTARU,L.SKRISOVSKA,AUTH 2 A.P.GOLOVANOV,J.STEVENIN,L.Y.LIAN,S.A.WILSON,AUTH 3 F.H.ALLAINTITL MOLECULAR BASIS OF RNA RECOGNITION AND TAP BINDINGTITL 2 BY THE SR PROTEINS SRP20 AND 9G8.REF EMBO J. V. 25 5126 2006REFN ISSN 0261-4189PMID 17036044DOI 10.1038/SJ.EMBOJ.7601385 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 87 |
| Number Of SNVs | 3 |
| Number Of Permutations | 74 |
| Optimal Distance Threshold | 6.0 |
| K Statistic | 0.333 |
| p-value | 0.36 |
COSMIC
| Number Of Residues | 87 |
| Number Of SNVs | 3 |
| Number Of Permutations | 18 |
| Optimal Distance Threshold | 17.0 |
| K Statistic | 0.333 |
| p-value | 1.0 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 3 |
| Number Of COSMIC SNVs | 3 |
| Optimal Distance Threshold | 6.0 |
| K Statistic | -0.333 |
| p-value | 0.501 |
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
