3MQP.A | BCL2A1

General Structure Information

PDB ID 3mqp
HGNC Gene Label(s) BCL2A1
Structure Name crystal structure of human bfl-1 in complex with noxa bh3 peptide, northeast structural genomics consortium target hr2930
Resolution 2.24Å
Reference AUTH R.GUAN,R.XIAO,L.ZHAO,T.B.ACTON,C.GELINAS,G.T.MONTELIONETITL CRYSTAL STRUCTURE OF HUMAN BFL-1 IN COMPLEX WITH NOXA BH3TITL 2 PEPTIDEREF TO BE PUBLISHEDREFN

Variant Set Distributions

ExAC Variants

Number Of Residues 150
Number Of SNVs 35
Number Of Permutations 9843
Optimal Distance Threshold 6.0
K Statistic 0.015
p-value 0.213
COSMIC

Number Of Residues 150
Number Of SNVs 5
Number Of Permutations 1205
Optimal Distance Threshold 16.0
K Statistic 0.1
p-value 0.239

Ripley’s K Analysis Plots

ExACCOSMIC

Variant Set Comparisons

Cosmic vs. ExAC

Number Of ExAC SNVs 35
Number Of COSMIC SNVs 5
Optimal Distance Threshold 20.0
K Statistic -0.233
p-value 0.632

Mapped Variants

[+] ExAC Missense Variants

[+] COSMIC Missense Variants