General Structure Information
| PDB ID | 2vm8 |
| HGNC Gene Label(s) | DPYSL2 |
| Structure Name | human crmp-2 crystallised in the presence of mg |
| Resolution | 1.9Å |
| Reference | AUTH V.MAJAVA,N.LOYTYNOJA,W.Q.CHEN,G.LUBEC,P.KURSULATITL CRYSTAL AND SOLUTION STRUCTURE, STABILITY ANDTITL 2 POST- TRANSLATIONAL MODIFICATIONS OF COLLAPSINTITL 3 RESPONSE MEDIATOR PROTEIN 2.REF FEBS J. V. 275 4583 2008REFN ISSN 1742-464XPMID 18699782DOI 10.1111/J.1742-4658.2008.06601.X |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 476 |
| Number Of SNVs | 78 |
| Number Of Permutations | 43458 |
| Optimal Distance Threshold | 9.0 |
| K Statistic | 0.036 |
| p-value | 0.4 |
COSMIC
| Number Of Residues | 476 |
| Number Of SNVs | 4 |
| Number Of Permutations | 82 |
| Optimal Distance Threshold | 15.0 |
| K Statistic | 0.167 |
| p-value | 1.0 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 78 |
| Number Of COSMIC SNVs | 4 |
| Optimal Distance Threshold | 21.0 |
| K Statistic | 0.369 |
| p-value | 0.582 |
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
