General Structure Information
| PDB ID | 4b87 |
| HGNC Gene Label(s) | DCLRE1A |
| Structure Name | crystal structure of human dna cross-link repair 1a |
| Resolution | 2.16Å |
| Reference | AUTH C.K.ALLERSTON,G.BERRIDGE,E.P.CARPENTER,G.KOCHAN,T.KROJER,AUTH 2 P.MAHAJAN,M.VOLLMAR,W.W.YUE,C.H.ARROWSMITH,A.EDWARDS,AUTH 3 C.BOUNTRA,F.VON DELFT,O.GILEADITITL CRYSTAL STRUCTURE OF HUMAN DNA CROSS-LINK REPAIR 1AREF TO BE PUBLISHEDREFN |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 335 |
| Number Of SNVs | 76 |
| Number Of Permutations | 13083 |
| Optimal Distance Threshold | 15.0 |
| K Statistic | 0.169 |
| p-value | 0.153 |
COSMIC
| Number Of Residues | 335 |
| Number Of SNVs | 4 |
| Number Of Permutations | 628 |
| Optimal Distance Threshold | 26.0 |
| K Statistic | 0.833 |
| p-value | 0.436 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 76 |
| Number Of COSMIC SNVs | 4 |
| Optimal Distance Threshold | 26.0 |
| K Statistic | 0.318 |
| p-value | 0.884 |
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
