General Structure Information
| PDB ID | 4osy |
| HGNC Gene Label(s) | ASRGL1 |
| Structure Name | structure of fully-cleaved glycine-bound human l-asparaginase protein |
| Resolution | 1.91Å |
| Reference | AUTH Y.SU,C.S.KARAMITROS,J.NOMME,T.MCSORLEY,M.KONRAD,A.LAVIETITL FREE GLYCINE ACCELERATES THE AUTOPROTEOLYTIC ACTIVATION OFTITL 2 HUMAN ASPARAGINASE.REF CHEM.BIOL. V. 20 533 2013REFN ISSN 1074-5521PMID 23601642DOI 10.1016/J.CHEMBIOL.2013.03.006 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 294 |
| Number Of SNVs | 77 |
| Number Of Permutations | 31770 |
| Optimal Distance Threshold | 7.0 |
| K Statistic | 0.026 |
| p-value | 0.825 |
COSMIC
| Number Of Residues | 294 |
| Number Of SNVs | 3 |
| Number Of Permutations | 67 |
| Optimal Distance Threshold | 23.0 |
| K Statistic | 0.333 |
| p-value | 0.983 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 77 |
| Number Of COSMIC SNVs | 3 |
| Optimal Distance Threshold | 25.0 |
| K Statistic | 0.412 |
| p-value | 0.755 |