1KHU.B | SMAD1

General Structure Information

PDB ID 1khu
HGNC Gene Label(s) SMAD1
Structure Name smad1 crystal structure reveals the details of bmp signaling pathway
Resolution 2.5Å
Reference AUTH B.Y.QIN,B.M.CHACKO,S.S.LAM,M.P.DE CAESTECKER,AUTH 2 J.J.CORREIA,K.LINTITL STRUCTURAL BASIS OF SMAD1 ACTIVATION BY RECEPTORTITL 2 KINASE PHOSPHORYLATION.REF MOL.CELL V. 8 1303 2001REFN ISSN 1097-2765PMID 11779505DOI 10.1016/S1097-2765(01)00417-8

Variant Set Distributions

ExAC Variants

Number Of Residues 197
Number Of SNVs 27
Number Of Permutations 12472
Optimal Distance Threshold 6.0
K Statistic 0.006
p-value 0.848

Mapped Variants

[+] ExAC Missense Variants