General Structure Information
| PDB ID | 3qxl |
| HGNC Gene Label(s) | RALGPS1 |
| Structure Name | crystal structure of the cdc25 domain from ral-specific guanine- nucleotide exchange factor ralgps1a |
| Resolution | 2.24Å |
| Reference | AUTH W.PENG,J.XU,X.GUAN,Y.SUN,X.C.ZHANG,X.LI,Z.RAOTITL STRUCTURAL STUDY OF THE CDC25 DOMAIN FROM RAL-SPECIFICTITL 2 GUANINE-NUCLEOTIDE EXCHANGE FACTOR RALGPS1A.REF PROTEIN CELL V. 2 308 2011REFN ISSN 1674-800XPMID 21494904DOI 10.1007/S13238-011-1036-Z |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 245 |
| Number Of SNVs | 32 |
| Number Of Permutations | 5673 |
| Optimal Distance Threshold | 19.0 |
| K Statistic | 0.244 |
| p-value | 0.227 |
COSMIC
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 32 |
| Number Of COSMIC SNVs | 3 |
| Optimal Distance Threshold | 30.0 |
| K Statistic | 0.387 |
| p-value | 1.0 |
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
