General Structure Information
| PDB ID | 1fpz |
| HGNC Gene Label(s) | CDKN3 |
| Structure Name | crystal structure analysis of kinase associated phosphatase (kap) with a substitution of the catalytic site cysteine (cys140) to a serine |
| Resolution | 2.0Å |
| Reference | AUTH H.SONG,N.HANLON,N.R.BROWN,M.E.NOBLE,L.N.JOHNSON,AUTH 2 D.BARFORDTITL PHOSPHOPROTEIN-PROTEIN INTERACTIONS REVEALED BYTITL 2 THE CRYSTAL STRUCTURE OF KINASE-ASSOCIATEDTITL 3 PHOSPHATASE IN COMPLEX WITH PHOSPHOCDK2.REF MOL.CELL V. 7 615 2001REFN ISSN 1097-2765PMID 11463386DOI 10.1016/S1097-2765(01)00208-8 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 178 |
| Number Of SNVs | 32 |
| Number Of Permutations | 3955 |
| Optimal Distance Threshold | 11.0 |
| K Statistic | 0.151 |
| p-value | 0.496 |
COSMIC
| Number Of Residues | 178 |
| Number Of SNVs | 3 |
| Number Of Permutations | 66 |
| Optimal Distance Threshold | 10.0 |
| K Statistic | 0.333 |
| p-value | 0.594 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 32 |
| Number Of COSMIC SNVs | 3 |
| Optimal Distance Threshold | 10.0 |
| K Statistic | 0.22 |
| p-value | 0.911 |
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
