General Structure Information
| PDB ID | 2uyy |
| HGNC Gene Label(s) | GLYR1 |
| Structure Name | structure of the cytokine-like nuclear factor n-pac |
| Resolution | 2.5Å |
| Reference | AUTH J.TICKLE,E.S.PILKA,G.BUNKOCZI,G.BERRIDGE,C.SMEE,AUTH 2 K.L.KAVANAGH,V.HOZJAN,F.H.NIESEN,E.PAPAGRIGORIOU,A.C.W.PIKE,AUTH 3 A.TURNBULL,C.H.ARROWSMITH,A.EDWARDS,M.SUNDSTROM,J.WEIGELT,AUTH 4 F.VON DELFT,U.OPPERMANNTITL THE STRUCTURE OF THE CYTOKINE-LIKE NUCLEAR FACTOR N-PACREF TO BE PUBLISHEDREFN |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 292 |
| Number Of SNVs | 50 |
| Number Of Permutations | 27337 |
| Optimal Distance Threshold | 21.0 |
| K Statistic | 0.439 |
| p-value | 0.113 |
COSMIC
| Number Of Residues | 292 |
| Number Of SNVs | 7 |
| Number Of Permutations | 5069 |
| Optimal Distance Threshold | 23.0 |
| K Statistic | 0.19 |
| p-value | 0.054 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 50 |
| Number Of COSMIC SNVs | 7 |
| Optimal Distance Threshold | 23.0 |
| K Statistic | -0.313 |
| p-value | 0.018 |
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
