General Structure Information
| PDB ID | 2vcv |
| HGNC Gene Label(s) | GSTA3 |
| Structure Name | glutathione transferase a3-3 in complex with glutathione and delta-4-androstene-3-17-dione |
| Resolution | 1.8Å |
| Reference | AUTH K.TARS,B.OLIN,B.MANNERVIKTITL STRUCTURAL BASIS FOR FEATURING OF STEROID ISOMERASETITL 2 ACTIVITY IN ALPHA CLASS GLUTATHIONE TRANSFERASES.REF J.MOL.BIOL. V. 397 332 2010REFN ISSN 0022-2836PMID 20083122DOI 10.1016/J.JMB.2010.01.023 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 219 |
| Number Of SNVs | 67 |
| Number Of Permutations | 24833 |
| Optimal Distance Threshold | 6.0 |
| K Statistic | 0.02 |
| p-value | 0.938 |
COSMIC
| Number Of Residues | 219 |
| Number Of SNVs | 3 |
| Number Of Permutations | 7 |
| Optimal Distance Threshold | 14.0 |
| K Statistic | 0.333 |
| p-value | 0.899 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 67 |
| Number Of COSMIC SNVs | 4 |
| Optimal Distance Threshold | 27.0 |
| K Statistic | -0.488 |
| p-value | 0.143 |
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
