General Structure Information
| PDB ID | 2edv |
| HGNC Gene Label(s) | FRMPD1 |
| Structure Name | solution structure of the pdz domain from human ferm and pdz domain containing 1 |
| Resolution | -1.0Å |
| Reference | AUTH K.SEIMIYA,C.KUROSAKI,M.YOSHIDA,F.HAYASHI,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE PDZ DOMAIN FROM HUMANTITL 2 FERM AND PDZ DOMAIN CONTAINING 1REF TO BE PUBLISHEDREFN |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 83 |
| Number Of SNVs | 32 |
| Number Of Permutations | 6305 |
| Optimal Distance Threshold | 6.0 |
| K Statistic | 0.04 |
| p-value | 0.865 |
COSMIC
| Number Of Residues | 83 |
| Number Of SNVs | 3 |
| Number Of Permutations | 77 |
| Optimal Distance Threshold | 13.0 |
| K Statistic | 0.667 |
| p-value | 0.542 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 32 |
| Number Of COSMIC SNVs | 3 |
| Optimal Distance Threshold | 13.0 |
| K Statistic | 0.31 |
| p-value | 0.81 |
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
