General Structure Information
| PDB ID | 4hon |
| HGNC Gene Label(s) | KDM4D |
| Structure Name | crystal structure of human jmjd2d/kdm4d in complex with an h3k9me3 peptide and 2-oxoglutarate |
| Resolution | 1.8Å |
| Reference | AUTH S.KRISHNAN,R.C.TRIEVELTITL STRUCTURAL AND FUNCTIONAL ANALYSIS OF JMJD2D REVEALSTITL 2 MOLECULAR BASIS FOR SITE-SPECIFIC DEMETHYLATION AMONG JMJD2TITL 3 DEMETHYLASES.REF STRUCTURE V. 21 98 2013REFN ISSN 0969-2126PMID 23219879DOI 10.1016/J.STR.2012.10.018 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 330 |
| Number Of SNVs | 57 |
| Number Of Permutations | 10106 |
| Optimal Distance Threshold | 15.0 |
| K Statistic | 0.112 |
| p-value | 0.001 |
COSMIC
| Number Of Residues | 330 |
| Number Of SNVs | 5 |
| Number Of Permutations | 698 |
| Optimal Distance Threshold | 16.0 |
| K Statistic | 0.1 |
| p-value | 0.878 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 57 |
| Number Of COSMIC SNVs | 5 |
| Optimal Distance Threshold | 31.0 |
| K Statistic | -0.136 |
| p-value | 0.972 |
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
