General Structure Information
| PDB ID | 3d8b |
| HGNC Gene Label(s) | FIGNL1 |
| Structure Name | crystal structure of human fidgetin-like protein 1 in complex with adp |
| Resolution | 2.0Å |
| Reference | AUTH T.KARLBERG,M.WISNIEWSKA,J.ANDERSSON,C.H.ARROWSMITH,AUTH 2 H.BERGLUND,R.D.BUSAM,R.COLLINS,L.G.DAHLGREN,A.M.EDWARDS,AUTH 3 S.FLODIN,A.FLORES,S.GRASLUND,M.HAMMARSTROM,A.JOHANSSON,AUTH 4 I.JOHANSSON,A.KALLAS,T.KOTENYOVA,L.LEHTIO,M.MOCHE,AUTH 5 M.E.NILSSON,P.NORDLUND,T.NYMAN,K.OLESEN,C.PERSSON,AUTH 6 J.SAGEMARK,A.G.THORSELL,L.TRESAUGUES,S.VAN DEN BERG,M.WELIN,AUTH 7 M.WIKSTROM,H.SCHULERTITL HUMAN FIDGETIN-LIKE PROTEIN 1.REF TO BE PUBLISHEDREFN |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 281 |
| Number Of SNVs | 87 |
| Number Of Permutations | 18017 |
| Optimal Distance Threshold | 18.0 |
| K Statistic | 0.218 |
| p-value | 0.018 |
COSMIC
| Number Of Residues | 281 |
| Number Of SNVs | 5 |
| Number Of Permutations | 2350 |
| Optimal Distance Threshold | 23.0 |
| K Statistic | 0.2 |
| p-value | 0.469 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 87 |
| Number Of COSMIC SNVs | 3 |
| Optimal Distance Threshold | 17.0 |
| K Statistic | -0.196 |
| p-value | 0.747 |
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
