General Structure Information
| PDB ID | 1wwc |
| HGNC Gene Label(s) | NTRK3 |
| Structure Name | nt3 binding domain of human trkc receptor |
| Resolution | 1.9Å |
| Reference | AUTH M.H.ULTSCH,C.WIESMANN,L.C.SIMMONS,J.HENRICH,M.YANG,D.REILLY,AUTH 2 S.H.BASS,A.M.DE VOSTITL CRYSTAL STRUCTURES OF THE NEUROTROPHIN-BINDING DOMAIN OFTITL 2 TRKA, TRKB AND TRKC.REF J.MOL.BIOL. V. 290 149 1999REFN ISSN 0022-2836PMID 10388563DOI 10.1006/JMBI.1999.2816 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 105 |
| Number Of SNVs | 22 |
| Number Of Permutations | 5477 |
| Optimal Distance Threshold | 6.0 |
| K Statistic | 0.022 |
| p-value | 0.95 |
COSMIC
| Number Of Residues | 105 |
| Number Of SNVs | 7 |
| Number Of Permutations | 1568 |
| Optimal Distance Threshold | 5.0 |
| K Statistic | 0.095 |
| p-value | 0.638 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 22 |
| Number Of COSMIC SNVs | 6 |
| Optimal Distance Threshold | 7.0 |
| K Statistic | 0.228 |
| p-value | 0.728 |
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
