General Structure Information
| PDB ID | 3cfv |
| HGNC Gene Label(s) | RBBP7 |
| Structure Name | structural basis of the interaction of rbap46/rbap48 with histone h4 |
| Resolution | 2.6Å |
| Reference | AUTH N.V.MURZINA,X.Y.PEI,W.ZHANG,M.SPARKES,AUTH 2 J.VICENTE-GARCIA,J.V.PRATAP,S.H.MCLAUGHLIN,AUTH 3 T.R.BEN-SHAHAR,A.VERREAULT,B.F.LUISI,E.D.LAUETITL STRUCTURAL BASIS FOR THE RECOGNITION OF HISTONE H4TITL 2 BY THE HISTONE-CHAPERONE RBAP46.REF STRUCTURE V. 16 1077 2008REFN ISSN 0969-2126PMID 18571423DOI 10.1016/J.STR.2008.05.006 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 381 |
| Number Of SNVs | 17 |
| Number Of Permutations | 3338 |
| Optimal Distance Threshold | 15.0 |
| K Statistic | 0.176 |
| p-value | 0.489 |
COSMIC
| Number Of Residues | 381 |
| Number Of SNVs | 11 |
| Number Of Permutations | 6570 |
| Optimal Distance Threshold | 21.0 |
| K Statistic | 0.491 |
| p-value | 0.304 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 17 |
| Number Of COSMIC SNVs | 8 |
| Optimal Distance Threshold | 29.0 |
| K Statistic | 0.287 |
| p-value | 0.618 |
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
