General Structure Information
| PDB ID | 2v7c |
| HGNC Gene Label(s) | NR1D2 |
| Structure Name | crystal structure of rev-erb beta |
| Resolution | 2.4Å |
| Reference | AUTH E.-J.WOO,D.G.JEONG,M.-Y.LIM,S.J.KIM,K.-J.KIM,AUTH 2 S.-M.YOON,B.-C.PARK,S.E.RYUTITL STRUCTURAL INSIGHT INTO THE CONSTITUTIVETITL 2 REPRESSION FUNCTION OF THE NUCLEAR RECEPTORTITL 3 REV-ERBBETAREF J.MOL.BIOL. V. 373 735 2007REFN ISSN 0022-2836PMID 17870090DOI 10.1016/J.JMB.2007.08.037 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 169 |
| Number Of SNVs | 38 |
| Number Of Permutations | 11803 |
| Optimal Distance Threshold | 6.0 |
| K Statistic | 0.031 |
| p-value | 0.892 |
COSMIC
| Number Of Residues | 169 |
| Number Of SNVs | 3 |
| Number Of Permutations | 108 |
| Optimal Distance Threshold | 16.0 |
| K Statistic | 0.667 |
| p-value | 0.262 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 38 |
| Number Of COSMIC SNVs | 3 |
| Optimal Distance Threshold | 19.0 |
| K Statistic | 0.593 |
| p-value | 0.255 |
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
