General Structure Information
| PDB ID | 1ldj |
| HGNC Gene Label(s) | CUL1 |
| Structure Name | structure of the cul1-rbx1-skp1-f boxskp2 scf ubiquitin ligase complex |
| Resolution | 3.0Å |
| Reference | AUTH N.ZHENG,B.A.SCHULMAN,L.SONG,J.J.MILLER,P.D.JEFFREY,AUTH 2 P.WANG,C.CHU,D.M.KOEPP,S.J.ELLEDGE,M.PAGANO,AUTH 3 R.C.CONAWAY,J.W.CONAWAY,J.W.HARPER,N.P.PAVLETICHTITL STRUCTURE OF THE CUL1-RBX1-SKP1-F BOXSKP2 SCFTITL 2 UBIQUITIN LIGASE COMPLEX.REF NATURE V. 416 703 2002REFN ISSN 0028-0836PMID 11961546DOI 10.1038/416703A |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 725 |
| Number Of SNVs | 46 |
| Number Of Permutations | 59842 |
| Optimal Distance Threshold | 32.0 |
| K Statistic | 0.229 |
| p-value | 0.155 |
COSMIC
| Number Of Residues | 725 |
| Number Of SNVs | 15 |
| Number Of Permutations | 9499 |
| Optimal Distance Threshold | 15.0 |
| K Statistic | 0.019 |
| p-value | 0.887 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 46 |
| Number Of COSMIC SNVs | 14 |
| Optimal Distance Threshold | 15.0 |
| K Statistic | -0.055 |
| p-value | 0.918 |