General Structure Information
| PDB ID | 3l4c |
| HGNC Gene Label(s) | DOCK1 |
| Structure Name | structural basis of membrane-targeting by dock180 |
| Resolution | 2.37Å |
| Reference | AUTH L.PREMKUMAR,A.A.BOBKOV,M.PATEL,L.JAROSZEWSKI,L.A.BANKSTON,AUTH 2 B.STEC,K.VUORI,J.F.COTE,R.C.LIDDINGTONTITL STRUCTURAL BASIS OF MEMBRANE TARGETING BY THE DOCK180TITL 2 FAMILY OF RHO FAMILY GUANINE EXCHANGE FACTORS (RHO-GEFS).REF J.BIOL.CHEM. V. 285 13211 2010REFN ISSN 0021-9258PMID 20167601DOI 10.1074/JBC.M110.102517 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 179 |
| Number Of SNVs | 40 |
| Number Of Permutations | 4318 |
| Optimal Distance Threshold | 7.0 |
| K Statistic | 0.055 |
| p-value | 0.168 |