1S1C.Y | ROCK1

General Structure Information

PDB ID 1s1c
HGNC Gene Label(s) ROCK1
Structure Name crystal structure of the complex between the human rhoa and rho-binding domain of human rocki
Resolution 2.6Å
Reference AUTH R.DVORSKY,L.BLUMENSTEIN,I.R.VETTER,M.R.AHMADIANTITL STRUCTURAL INSIGHTS INTO THE INTERACTION OF ROCKITITL 2 WITH THE SWITCH REGIONS OF RHOA.REF J.BIOL.CHEM. V. 279 7098 2004REFN ISSN 0021-9258PMID 14660612DOI 10.1074/JBC.M311911200

Variant Set Distributions

ExAC Variants

Number Of Residues 68
Number Of SNVs 11
Number Of Permutations 4262
Optimal Distance Threshold 12.0
K Statistic 0.291
p-value 0.393

Mapped Variants

[+] ExAC Missense Variants