4A63.D | TP53BP2

General Structure Information

PDB ID 4a63
HGNC Gene Label(s) TP53BP2
Structure Name crystal structure of the p73-aspp2 complex at 2.6a resolution
Resolution 2.27Å
Reference AUTH P.CANNING,F.VON DELFT,A.N.BULLOCKTITL STRUCTURAL BASIS FOR ASPP2 RECOGNITION BY THE TUMORTITL 2 SUPPRESSOR P73.REF J.MOL.BIOL. V. 423 515 2012REFN ISSN 0022-2836PMID 22917970DOI 10.1016/J.JMB.2012.08.005

Variant Set Distributions

ExAC Variants

Number Of Residues 196
Number Of SNVs 32
Number Of Permutations 12730
Optimal Distance Threshold 7.0
K Statistic 0.03
p-value 0.965
COSMIC

Ripley’s K Analysis Plots

ExACCOSMIC

Variant Set Comparisons

Cosmic vs. ExAC

Mapped Variants

[+] ExAC Missense Variants

[+] COSMIC Missense Variants