General Structure Information
| PDB ID | 3orh |
| HGNC Gene Label(s) | GAMT |
| Structure Name | human guanidinoacetate n-methyltransferase with sah |
| Resolution | 1.86Å |
| Reference | AUTH H.WU,A.DONG,H.ZENG,P.LOPPNAU,M.SUNDSTROM,C.H.ARROWSMITH,AUTH 2 A.M.EDWARDS,A.BOCHKAREV,A.N.PLOTNIKOVTITL THE CRYSTAL STRUCTURE OF HUMAN GUANIDINOACETATETITL 2 N-METHYLTRANSFERASE WITH SAHREF TO BE PUBLISHEDREFN |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 230 |
| Number Of SNVs | 68 |
| Number Of Permutations | 4740 |
| Optimal Distance Threshold | 6.0 |
| K Statistic | 0.023 |
| p-value | 0.402 |
ClinVar
| Number Of Residues | 230 |
| Number Of SNVs | 8 |
| Number Of Permutations | 553 |
| Optimal Distance Threshold | 8.0 |
| K Statistic | 0.0 |
| p-value | 0.581 |
COSMIC
| Number Of Residues | 230 |
| Number Of SNVs | 4 |
| Number Of Permutations | 292 |
| Optimal Distance Threshold | 11.0 |
| K Statistic | 0.333 |
| p-value | 0.231 |
Ripley’s K Analysis Plots
ExACClinVarCOSMIC
Variant Set Comparisons
ClinVar vs. ExAC
| Number Of ExAC SNVs | 68 |
| Number Of ClinVar SNVs | 8 |
| Optimal Distance Threshold | 8.0 |
| K Statistic | -0.046 |
| p-value | 0.435 |
Cosmic vs. ExAC
| Number Of ExAC SNVs | 68 |
| Number Of COSMIC SNVs | 4 |
| Optimal Distance Threshold | 11.0 |
| K Statistic | 0.225 |
| p-value | 0.706 |