1UJY.A | ARHGEF6

PDB ID	1ujy
HGNC Gene Label(s)	ARHGEF6
Structure Name	solution structure of sh3 domain in rac/cdc42 guanine nucleotide exchange factor(gef) 6
Resolution	-1.0Å
Reference	AUTH F.HE,Y.MUTO,H.UDA,S.KOSHIBA,M.SHIROUZU,T.TERADA,AUTH 2 T.KIGAWA,M.INOUE,T.YABUKI,M.AOKI,E.SEKI,T.MATSUDA,AUTH 3 H.HIROTA,M.YOSHIDA,N.KOBAYASHI,A.TANAKA,T.OSANAI,AUTH 4 Y.MATSUO,O.OHARA,T.NAGASE,R.KIKUNO,M.NAGAYAMA,AUTH 5 S.YOKOYAMATITL SOLUTION STRUCTURE OF SH3 DOMAIN IN RAC/CDC42TITL 2 GUANINE NUCLEOTIDE EXCHANGE FACTOR(GEF) 6REF TO BE PUBLISHEDREFN

ExAC Variants

Position	Variant	AA Change	PDB Chain Position	Structure Coordinates
X:135825914		I>R	A:12	(-0.13, -4.25, 6.43)
X:135825915		I>V	A:12	(-0.13, -4.25, 6.43)
X:135825895		N>K	A:18	(-14.82, 8.65, 4.64)
X:135825884		T>N	A:22	(-11.36, 9.44, -8.52)
X:135825870		L>V	A:27	(-7.89, 1.39, -3.81)
X:135825852		D>N	A:33	(-10.12, -0.12, 5.53)
X:135825825		E>K	A:42	(8.75, 7.97, -4.88)
X:135825797		N>S	A:51	(-10.70, -5.62, 2.52)
X:135825790		R>S	A:53	(-12.27, -2.01, -4.06)
X:135825758	rs139422484	E>G	A:64	(2.32, 2.65, 8.21)

1UJY.A | ARHGEF6.