General Structure Information
| PDB ID | 1by1 |
| HGNC Gene Label(s) | ARHGEF7 |
| Structure Name | dbl homology domain from beta-pix |
| Resolution | -1.0Å |
| Reference | AUTH B.AGHAZADEH,K.ZHU,T.J.KUBISESKI,G.A.LIU,T.PAWSON,AUTH 2 Y.ZHENG,M.K.ROSENTITL STRUCTURE AND MUTAGENESIS OF THE DBL HOMOLOGYTITL 2 DOMAINREF NAT.STRUCT.BIOL. V. 5 1098 1998REFN ISSN 1072-8368PMID 9846881DOI 10.1038/4209 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 208 |
| Number Of SNVs | 53 |
| Number Of Permutations | 15250 |
| Optimal Distance Threshold | 12.0 |
| K Statistic | 0.089 |
| p-value | 0.071 |
COSMIC

Ripley’s K Analysis Plots
ExACCOSMIC


Variant Set Comparisons
Cosmic vs. ExAC

Pathogenic Proximity Analysis
COSMIC PathProx Analysis

