General Structure Information
| PDB ID | 4ed5 |
| HGNC Gene Label(s) | ELAVL1 |
| Structure Name | crystal structure of the two n-terminal rrm domains of hur complexed with rna |
| Resolution | 2.0Å |
| Reference | AUTH H.WANG,F.ZENG,Q.LIU,H.LIU,Z.LIU,L.NIU,M.TENG,X.LITITL THE STRUCTURE OF THE ARE-BINDING DOMAINS OF HU ANTIGEN RTITL 2 (HUR) UNDERGOES CONFORMATIONAL CHANGES DURING RNA BINDING.REF ACTA CRYSTALLOGR.,SECT.D V. 69 373 2013REFN ISSN 0907-4449PMID 23519412DOI 10.1107/S0907444912047828 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 169 |
| Number Of SNVs | 14 |
| Number Of Permutations | 6455 |
| Optimal Distance Threshold | 11.0 |
| K Statistic | 0.055 |
| p-value | 0.266 |
COSMIC
| Number Of Residues | 169 |
| Number Of SNVs | 7 |
| Number Of Permutations | 1590 |
| Optimal Distance Threshold | 5.0 |
| K Statistic | 0.095 |
| p-value | 0.094 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 14 |
| Number Of COSMIC SNVs | 6 |
| Optimal Distance Threshold | 5.0 |
| K Statistic | 0.111 |
| p-value | 0.238 |
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
