General Structure Information
| PDB ID | 3n1p |
| HGNC Gene Label(s) | IHH |
| Structure Name | crystal structure of ihhn bound to bocfn3 |
| Resolution | 2.7Å |
| Reference | AUTH J.M.KAVRAN,M.D.WARD,O.O.OLADOSU,S.MULEPATI,D.J.LEAHYTITL ALL MAMMALIAN HEDGEHOG PROTEINS INTERACT WITH CDO AND BOCTITL 2 IN A CONSERVED MANNER.REF J.BIOL.CHEM. 2010REFN ESSN 1083-351XPMID 20519495DOI 10.1074/JBC.M110.131680 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 153 |
| Number Of SNVs | 20 |
| Number Of Permutations | 7639 |
| Optimal Distance Threshold | 8.0 |
| K Statistic | 0.089 |
| p-value | 0.964 |
ClinVar
| Number Of Residues | 153 |
| Number Of SNVs | 8 |
| Number Of Permutations | 2831 |
| Optimal Distance Threshold | 7.0 |
| K Statistic | 0.214 |
| p-value | 0.008 |
Ripley’s K Analysis Plots
ExACClinVar
Variant Set Comparisons
ClinVar vs. ExAC
| Number Of ExAC SNVs | 20 |
| Number Of ClinVar SNVs | 8 |
| Optimal Distance Threshold | 11.0 |
| K Statistic | 0.276 |
| p-value | 0.002 |
Pathogenic Proximity Analysis
ClinVar PathProx Analysis
