General Structure Information
| PDB ID | 3u82 |
| HGNC Gene Label(s) | PVRL1 |
| Structure Name | binding of herpes simplex virus glycoprotein d to nectin-1 exploits host cell adhesion |
| Resolution | 3.16Å |
| Reference | AUTH N.ZHANG,J.YAN,G.LU,Z.GUO,Z.FAN,J.WANG,Y.SHI,J.QI,G.F.GAOTITL BINDING OF HERPES SIMPLEX VIRUS GLYCOPROTEIN D TO NECTIN-1TITL 2 EXPLOITS HOST CELL ADHESION.REF NAT COMMUN V. 2 577 2011REFN ESSN 2041-1723PMID 22146396DOI 10.1038/NCOMMS1571 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 300 |
| Number Of SNVs | 80 |
| Number Of Permutations | 62186 |
| Optimal Distance Threshold | 30.0 |
| K Statistic | 0.399 |
| p-value | 0.323 |
COSMIC
| Number Of Residues | 300 |
| Number Of SNVs | 3 |
| Number Of Permutations | 33 |
| Optimal Distance Threshold | 35.0 |
| K Statistic | 0.333 |
| p-value | 1.0 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 80 |
| Number Of COSMIC SNVs | 3 |
| Optimal Distance Threshold | 30.0 |
| K Statistic | -0.399 |
| p-value | 0.903 |
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
