General Structure Information
| PDB ID | 2d7o |
| HGNC Gene Label(s) | FLNC |
| Structure Name | solution structure of the 17th filamin domain from human filamin c |
| Resolution | -1.0Å |
| Reference | AUTH T.TOMIZAWA,T.KIGAWA,S.KOSHIBA,M.INOUE,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE 17TH FILAMIN DOMAIN FROMTITL 2 HUMAN FILAMIN CREF TO BE PUBLISHEDREFN |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 98 |
| Number Of SNVs | 18 |
| Number Of Permutations | 12496 |
| Optimal Distance Threshold | 8.0 |
| K Statistic | 0.131 |
| p-value | 0.596 |
COSMIC
| Number Of Residues | 98 |
| Number Of SNVs | 3 |
| Number Of Permutations | 27 |
| Optimal Distance Threshold | 10.0 |
| K Statistic | 0.667 |
| p-value | 0.098 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 18 |
| Number Of COSMIC SNVs | 3 |
| Optimal Distance Threshold | 13.0 |
| K Statistic | 0.706 |
| p-value | 0.126 |
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
